Glomerulonephritis to Renal Cell Carcinoma: Diagnostic Dilemma with Successful Management of a 8 Year Old Boy

MOHAMMED MARUF-UL-QUADER1, BASANA RANI MUHURI2, AKM REZAUL KARIM3, SHARMIN SULTANA4, SAYED MESBAHUL HOQUE5

Introduction
Renal cell carcinoma (RCC) is a malignancy thought to arise from epithelial cells of the renal tubule. Although RCC accounts for 2% to 3% of all adult malignancies, it occurs rarely in children.1 The incidence of this tumor in childhood is estimated to be from 0.1% to 0.3% of all neoplasms and from 1.8% to 6.3% of all malignant renal tumors.2-5 The Third National Cancer Survey on US children reported an incidence of only four cases of RCC per year compared with 117 per year of Wilms’ tumor in pediatric age.5 Most experience with pediatric RCC limited with case reports or case series consisting of small number of cases. We are reporting a case of 8 year old boy who was prsented with intermittent gross and haematuria proteinurea. Initially suspected as a case of IgA
nephropathy. But subsequently diagnosed as RCCClear cell type-a, rare pathological type in children.He was successfully managed by surgery, chemotherapy and radiotherapy.

 

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