Abstract
Celiae disease is an immunological disorder precipitated by gluten in genetically
susceptible persons. Its prevalence is not known in Bangladesh because of
unavailability of its screening test. There is diversity in the presentation of celiac
disease. Two children of 5 and 8 years of age who were diagnosed as celiac disease
are reported here. One presented typically with chronic diarrhoea & growth failure.
Another child presented with features of chronic liver disease. In both the cases IgA
tTGA were positive and duodenal biopsy showed villous atrophy. After diagnosis,
both the patients were kept on gluten free diet (GFD). After six months of GFD, IgA
tTGA came down to normal in both the cases. They were then given gluten containing
diet again & after few months IgA tTGA again raised in both the cases. Thereafter
the cases were finally diagnosed as celiac disease and were advised life long gluten
free diet. Celiac disease is not uncommon in Bangladesh and screening test should
be done to diagnose or rule out celiac disease when there is a suspicion.
Key words: Bangladesh, Celiac disease, Case series, Gluten.